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ARIScience is RESHAPING THE FUTURE OF DRUG DISCOVERY

Identifying new cures for societal diseases through AI and Quantum Chemistry (AI+QQ) 

Our novel in-silico platform unites AI, quantum chemistry, computer vision and bio-chemistry to design and discover molecule compounds that interrupt disease pathways. We call this novel process: AI+QQ.

 

Assessed via established in vitro and in vivo assays, these small molecule compounds interrupt proteins allosterically, directly or formatively.

 

We are pursuing treatments for prevalent neurodegenerative, inflammatory and infectious diseases by focusing on the interruption of aberrant, overexpressed or pathogenic proteins.

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We are thrilled to announce that in April of 2023 we were awarded an advanced protein impact via small molecule research contract by the United States Biomedical Advanced Research and Development Agency. In October 2024 we successfully completed this BARDA project.

Bleeding-Edge Technology

Interrupt Proteins Like Never Before

Our novel in silico quasi quantum calculation methodology combined with a unique computation-first approach and diverse, purpose-driven team of experts delivers unparalleled results. Merging traditionally disparate scientific disciplines and utilizing cutting-edge technology and methodologies allows us to efficiently iterate and refine drug candidates, leading to higher success rates and a faster time-to-societal-impact for our clients. Our leading approach and expertise have resulted in a proven track record of success, and we are dedicated to bringing advanced science driven therapeutics to patients.

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Drug Discovery Process

Learn how our unique AI+QQ drug discovery process addresses the burden of disease on society. For more detailed information click here.

Drug Discovery

1

Predict and construct organic compounds that can directly or allosterically interrupt proteins in biological pathways using in silico methodology.

2

Confirm in silico results through in vitro assays.

3

Iterate and optimize compounds using derivative molecules based on in vitro results.

4

Confirm results through in vivo small animal models, typically murine models.

5

Candidate drugs are taken to FIH trials in in vivo test results are positive.

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August 22, 2025
More from our wet lab work: Prediction from our AI+QQ in silico process showing actual in vitro inhibition effect on another specific human protease.
AI+QQ Progress Report #20
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August 15, 2025
Our latest AI+QQ prediction shows actual CNS ion channel potentiation via in vitro functional assay, setting up a lead candidate for further optimization.
AI+QQ Progress Report #19
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July 30, 2025
More from our wet lab work: Prediction from our AI+QQ in silico process showing actual in vitro inhibition effect on another specific human protease (two candidates in diagram)
AI+QQ Progress Report #18
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July 1, 2025
Another AI+QQ prediction – showing protease potentiation non-trivial effect.
AI+QQ Progress Report #17
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June 30, 2025
Latest from the wet labs. Prediction from our AI+QQ in silico process showing actual in vitro inhibition effect on another specific human protease.
AI+QQ Progress Report #16
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June 15, 2025
A new AI+QQ prediction showing a CNS ion channel potentiation non-trivial effect.
AI+QQ Progress Report #15
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Get in Touch

Interested in our AI+QQ focused or end-to-end services? Have a question for the team? Reach out to us.

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About

At ARIScience we use our AI+QQ process to unify AI, quantum chemistry, and biochemistry to discover new therapeutics to improve human health and reduce disease burden.

Contact

Tel: ‭(774) 421-9001‬

148 Commonwealth Rd #5138 Wayland, MA 01778

© 2023 ARIScience. All rights reserved.

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